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Search Result

Search Results for " k 19 "

Targets

Others

27

Compounds

2

Natural Products

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T8936 Proteinase K proteinase K for tritirachium album,Protease K Others
Proteinase K (proteinase K for tritirachium album) is a nonspecific serine protease that is useful for general digestion of proteins. It is active in the presence of SDS or urea and over a wide range of pH (4-12), salt c...
T21254 Vonoprazan Fumarate TAK-438,TAK 438,Vonoprazan Fumurate,TAK438 Proton pump
Vonoprazan Fumarate (TAK438) , a novel potassium-competitive acid blocker, inhibits gastric acid secretion. Vonoprazan Fumarate (TAK438) inhibited H+,K+-ATPase activity in porcine gastric microsomes with IC50 value of 19...
TQ0319 Ripasudil K-115,Ripasudil hydrochloride dihydrate ROCK
Ripasudil (Ripasudil hydrochloride dihydrate) (K-115) hydrochloride dihydrate is a specific ROCK inhibitor (IC50s: 51/19 nM for ROCK1/ROCK2).
T14366 AZ10606120 dihydrochloride P2X Receptor
AZ10606120 dihydrochloride is a selectable, potent, high-affinity receptor antagonist with K D values of 1.4 and 19 nM at human and rat P2X 7 receptors, respectively. AZ10606120 dihydrochloride inhibits tumor growth and ...
T8388 Vonoprazan TAK-438 (free base) Proton pump
Vonoprazan (TAK-438 (free base)) is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and reflux esophagitis
T2404 Vonoprazan fumarate TAK-438 ATPase
Vonoprazan fumarate (TAK-438) is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase.
T0825 Ebselen SPI-1005,PZ-51,CCG-39161 Phosphatase , Virus Protease , Calcium Channel , COX , HIV Protease
Ebselen (CCG-39161) is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimetic and is thereby able to prevent cellular damage induced b...
T72330 Antibacterial agent 19
Antibacterial agent 19 exhibits strong activity against K. pneumoniae, (M-R) S. aureus, and (M-R,V-R) S. aureus, demonstrating minimum inhibitory concentrations (MICs) of 0.022 mg/mL for both K. pneumoniae and (M-R) S. a...
T40893 Estrogen receptor modulator 6
Estrogen receptor modulator 6 (compound 3a) is a highly specific and potent agonist of the estrogen receptor (ER) β with a remarkable affinity (K i = 0.44 nM). This compound exhibits an impressive 19-fold selectivity for...
T61491 (R)-ND-336
(R)-ND-336 is a highly potent and selective MMP-9 inhibitor, displaying a K i value of 19 nM. It also exhibits inhibitory activity against MMP-2 (K i = 127 nM) and MMP-14 (K i =119 nM). With its significant potential, (R...
T79648 CDK2-IN-19 CDK
CDK2-IN-19 (Compound 32) is a selective, orally active inhibitor of CDK2 (K i: 0.18 nM) that exhibits anticancer activity in mice with OVCAR3 tumors [1].
T79325 5-HT6 agonist 1 5-HT Receptor
Compound 19, a 5-HT6 agonist with an affinity (K i : 5 nM), exhibits antidepressant-like effects and enhances cognitive function while also inhibiting platelet aggregation. It demonstrates high metabolic stability [1].
T73372 GNE-2256
GNE-2256, also known as molecule 19, is an orally active compound that inhibits Interleukin 1 receptor-associated kinase 4 (IRAK4) with a K i of 1.4 nM and has an IL-6 inhibition concentration (IC50) of 190 nM.
T79373 A3AR agonist 2 Adenosine Receptor
Compound 19, a selective A3 Adenosine Receptor (A3AR) agonist (K i : 22.1 nM), effectively stimulates β-arrestin2 recruitment with an EC 50 value of 4.36 nM. This compound is utilized in research pertaining to inflammato...
T7492 Ripasudil free base K-115 (free base) ROCK , Antibacterial
Ripasudil free base (K-115 (free base)) is a selective and potent ROCK inhibitor, is a novel and potent antiglaucoma agent.
T61643 Vonoprazan hydrochloride
Vonoprazan hydrochloride, a proton pump inhibitor (PPI), effectively acts as a potassium-competitive acid blocker (P-CAB) with potent antisecretory activity. It notably inhibits H+,K+-ATPase activity in porcine gastric m...
T9686 YH-53
YH-53 is a potent 3CLpro inhibitor, exhibiting K i values of 6.3 nM and 34.7 nM against SARS-CoV-1 3CLpro and SARS-CoV-2 3CLpro, respectively. This peptidomimetic compound, characterized by its unique benzothiazolyl keto...
T37285 1-thio-β-D-Glucose Tetraacetate
1-thio-β-D-Glucose tetraacetate is a building block.1,2It has been used in the synthesis of aromatic glucosinolates with anti-inflammatory activity, as well as glucosylated poly(pentafluorostyrene) derivatives for coatin...
T38385 IT-143B
IT-143B is a bacterial metabolite that has been found in S. iakyrus.1 It inhibits the proliferation of OS-RC-2 and ACHN cancer cells (IC50s = 22 and 98 μM, respectively). |1. Li, K., Liang, Z., Chen, W., et al. Iakyricid...
TMIH-0601 Vonoprazan-d3
Vonoprazan-d3 is a deuterated compound of Vonoprazan. Vonoprazan has a CAS number of 881681-00-1. Vonoprazan is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduoden...
TMIH-0602 Vonoprazan-d4
Vonoprazan-d4 is a deuterated compound of Vonoprazan. Vonoprazan has a CAS number of 881681-00-1. Vonoprazan is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduoden...
T36999 7(S),17(S)-dihydroxy-8(E),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid
Novel oxylipins, referred to as docosanoids, have been derived from C22polyunsaturated fatty acids 7(S),17(S)-dihydroxy-8(E),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic acid (7(S),17(S)-hydroxy DPA) is a DPA-derived analog ...
T37065 6-Chloro-2-fluoropurine
6-Chloro-2-fluoropurine is a heterocyclic building block.1,2It has been used in the synthesis of purine nucleosides that inhibit cyclin-dependent kinases (CDKs)in vitro.16-Chloro-2-fluoropurine has also been used in the ...
T35533 6-Hydroxypyridin-3-ylboronic Acid
6-Hydroxypyridin-3-ylboronic acid is a heterocyclic building block.1,2It has been used in the synthesis of non-nucleoside inhibitors of hepatitis C virus (HCV) RNA-dependent RNA polymerase nonstructural protein 5B (NS5B)...
T35591 Guanfacine-13C,15N3 Guanfacine-13C,15N3
Guanfacine-13C,15N3is intended for us as an internal standard for the quantification of guanfacine by GC- or LC-MS. Guanfacine is an α2-adrenergic receptor (α2-AR) agonist with Kivalues of 93, 1,380, and 3,890 nM for α2A...
T36722 Deltorphin II (trifluoroacetate salt)
Deltorphin II is a peptide agonist of δ2-opioid receptors.1,2It is selective for δ-opioid receptors over μ- and κ-opioid receptors in radioligand bindings assays (Kis = 0.0033, >1, and >1 μM, respectively) and induces [3...
T36055 Nitisinone-13C6 Nitisinone-13C6
Nitisinone-13C6is intended for use as an internal standard for the quantification of nitisinone by GC- or LC-MS. Nitisinone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD), which converts 4-hydroxyphenylpyr...

Compounds

Proteinase K
T8936
Synonym: proteinase K for tritirachium album,Protease K
Target: Others
Vonoprazan Fumarate
T21254
Synonym: TAK-438,TAK 438,Vonoprazan Fumurate,TAK438
Target: Proton pump
Ripasudil
TQ0319
Synonym: K-115,Ripasudil hydrochloride dihydrate
Target: ROCK
AZ10606120 dihydrochloride
T14366
Synonym:
Target: P2X Receptor
Vonoprazan
T8388
Synonym: TAK-438 (free base)
Target: Proton pump
Vonoprazan fumarate
T2404
Synonym: TAK-438
Target: ATPase
Ebselen
T0825
Synonym: SPI-1005,PZ-51,CCG-39161
Target: Phosphatase, Virus Protease, Calcium Channel, COX, HIV Protease
Antibacterial agent 19
T72330
Synonym:
Target:
Estrogen receptor modulator 6
T40893
Synonym:
Target:
(R)-ND-336
T61491
Synonym:
Target:
CDK2-IN-19
T79648
Synonym:
Target: CDK
5-HT6 agonist 1
T79325
Synonym:
Target: 5-HT Receptor
GNE-2256
T73372
Synonym:
Target:
A3AR agonist 2
T79373
Synonym:
Target: Adenosine Receptor
Ripasudil free base
T7492
Synonym: K-115 (free base)
Target: ROCK, Antibacterial
Vonoprazan hydrochloride
T61643
Synonym:
Target:
YH-53
T9686
Synonym:
Target:
1-thio-β-D-Glucose Tetraacetate
T37285
Synonym:
Target:
IT-143B
T38385
Synonym:
Target:
Vonoprazan-d3
TMIH-0601
Synonym:
Target:
Vonoprazan-d4
TMIH-0602
Synonym:
Target:
7(S),17(S)-dihydroxy-8(E),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid
T36999
Synonym:
Target:
6-Chloro-2-fluoropurine
T37065
Synonym:
Target:
6-Hydroxypyridin-3-ylboronic Acid
T35533
Synonym:
Target:
Guanfacine-13C,15N3
T35591
Synonym: Guanfacine-13C,15N3
Target:
Deltorphin II (trifluoroacetate salt)
T36722
Synonym:
Target:
Nitisinone-13C6
T36055
Synonym: Nitisinone-13C6
Target:
Cat No. Product Name Synonyms Targets
T35609 19-O-Acetylchaetoglobosin A
19-O-Acetylchaetoglobosin A is a fungal metabolite originally isolated fromC. globosumthat has actin polymerization inhibitory and cytotoxic activities.1,2It inhibits actin polymerization in a cell-free assay when used a...
T38069 Aquastatin A
Aquastatin A is a fungal metabolite originally isolated fromF. aquaeductuumthat has diverse biological activities.1It is active againstS. aureus(MIC = 32 μg/ml) and inhibits enoyl-acyl carrier protein reductase (Fabl; IC...

Natural Products

19-O-Acetylchaetoglobosin A
T35609
Synonym:
Target:
Aquastatin A
T38069
Synonym:
Target:

Recombinant Proteins

Species：
Canine (1)
Expression System：
E. coli (1)
Tag：
N-His (1)
Cat No. Product Name Species Expression System
TMPK-00687 keratin, type I cytoskeletal 19 (310-399) Protein, Canine, Recombinant (His) Canine E. coli
Keratin 19 (K19) belongs to the keratin family of proteins, which maintains structural integrity of epithelia. In cancer, K19 is highly expressed in several types where it serves as a diagnostic marker.
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